RRP ISA Survey Results

    (Important Disclaimer)


    Resistance to ART (cautionary note)

    One important word of caution.

    ART works by way of the so-called transferrin receptors on the cell wall. These receptors exist in HPV tumors such as RRP, and they also exist in the malaria parasite. Malaria has evolved ways with which to evade treatment with ART, however, which is why doctors are now urging treatment for malaria with several different drugs, including ART. Because of this phenomenon, there is excellent reason to suppose that RRP could also develop strategies to resist ART.

    Patients or physicians using very low dose ART are taking a risk that the papillomas will develop a resistance to treatment, which will forever close the door to effective treatment with ART. This is a very serious issue, and while we are only speculating here, resistance in the malaria parasite provides evidence that this may not just be possible, but also probable.

    If you or your physician is using ART, you would do well to read our guidelines carefully. We know that patients following these guidelines have reported results that not just showed efficacy, but in many cases showed spectacular results. As far as I know, use of much lower dosing may be (?) ineffective or worse.

    Stepping down the dose radically out of an over-abundance of caution relative to safety--when safety at this dose level for artemisinin and artesunate has not actually been identified as an issue according to ART experts with whom we have consulted--may turn out to be bad for the patient.

    Please read this everything in this section very carefully. Do discuss this issue with any physician who recommends dosing with significantly lower doses of ART.